Cialis Information, Where To Buy Cialis Information, Online Cialis Information

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Cialis Information - the following Cialis information section addresses the most common questions associated with the use of Cialis for erection enhancement:


What is Cialis?

Cialis represents the longest lasting erectile enhancement drug on the market today. Cialis enhances erections up to 36 hours following a single dose.   Cialis has been approved by the European Commission for the treatment of erectile dysfunction and is now available throughout Europe.

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Why is Cialis sometimes referred to as tadalafil?

Tadalafil is the generic name for Cialis. The generic name represents the medications nonproprietary or chemical name, whereas, the brand name is the name a pharmaceutical give to a medication for marketing purposes.

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What is the appropriate dose of Cialis?

During clinical testing Cialis was administered in 10mg or 20mg doses. For most men the 10mg dose is sufficient to substantially enhance erections. Most doctors, concur buy the Cialis 20mg dose and split the tablet in half taking just 10mg of Cialis. Lilly pharmaceuticals charges the same price for both the Cialis 20mg tablets and the 10mg tablets.

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What are the results of the clinical trials concerning the percentage of men who had improved erections while taking Cialis?

The Phase III study examined the safety and efficacy of "on-demand" Cialis treatment in 196 men suffering from mild-to-severe ED(1). Men in the study were randomized to receive up to 20 mg of Cialis or placebo over a 12-week period. Men were free to take their study medication without restrictions on food or alcohol consumption and to have sex with their partners at the time of their choosing after each dose.

Results showed that 95 percent of men taking Cialis 10 mg reported significantly improved erections compared with baseline. In addition, 78 percent of intercourse attempts recorded by all men on Cialis 10 mg were successful. Importantly, 68 percent of men with ED treated with Cialis 10 mg achieved an erectile function score experts consider "normal" for healthy men as measured by the International Index of Erectile Function (IIEF).

On the 10 mg dose, 92 percent of men reported improved erections, and 90 percent of intercourse attempts were successful. Forty-two percent of men taking the 10 mg dose achieved IIEF scores in the normal range. Fifty-four percent of patients on placebo in the study reported improved erections, while 43 percent of their attempts were successful. Twenty percent of men taking placebo (sugar pill) attained IIEF scores in the "normal" range.

In this study, side effects were mild to moderate, and their incidence diminished with continued treatment. The most commonly reported side effects were backache, muscle ache and upset stomach. There were no clinically significant changes in blood pressure, heart rate, electrocardiograms or laboratory tests attributable to treatment with Cialis.

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How long does it take to notice the effects of Cialis once I take the medication?

During clinical studies most men were able to achieve an erection within twenty minutes of taking Cialis.
How long does the effects of Cialis last?

In a Phase III clinical study designed to evaluate the efficacy of Cialis at specific time points after dosing, 348 men with mild-to-severe ED were randomly assigned to receive Cialis 10 mg (n=175) or placebo (n=173) over approximately an eight-week period. Patients were instructed to attempt intercourse with their partners on four specific occasions: on two occasions at 24 hours after dosing and on two occasions at 36 hours after dosing. The primary endpoint was the percentage of successful sexual intercourse attempts.

"Cialis was statistically superior to placebo in enabling men with ED to have successful intercourse at 24 or 36 hours after taking the drug and showed a consistent effect at both time points," said Raymond Rosen, Ph.D., study author and director of the Program in Human Sexuality.

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How does Cialis work?

In technical terms Cialis exerts its action by effecting two enzymes, Cyclic guanosine monophosphate (cGMP) and phosphodiesterase type 5 (PDE5) that play important roles in erectile function. Sexual stimulation triggers the local release of nitric oxide (NO) from nerves and endothelial cells in the penis. NO stimulates an enzyme that catalyzes formation of cGMP from the nucleotide guanosine 5-triphospate (GTP) in the penile blood vessels and corpus cavernosum walls.

The cGMP causes vasodilation of arteries, allowing the influx of blood into the corpus cavernosum. Increased blood flow into the penis causes the erectile tissue to expand. When the erectile tissue has expanded sufficiently, the veins draining the corpus cavernosum become compressed. This decreases the outflow of blood from the penis, and the blood remains in the corpus cavernosum to keep the penis erect.

The enzyme PDE5 eventually causes degradation of the cGMP, and the erection ends.

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How much time must surpass before Cialis is effective?

Cialis is rapidly absorbed. Most patients in clinical trial reported that Cialis produced positive effects within twenty minutes.

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What are the precautions/warnings concerning Cialis?

Men who are taking medicines that contain nitrates (Nitroglycerin) of any kind must never use Cialis. Patients should not take Cialis even if you only take nitroglycerin medication occasionally. There is also a potential for cardiac risk during sexual activity in patients with preexisting cardiovascular disease. Therefore, Cialis should not be used in men where sexual activity is inadvisable because of their underlying cardiovascular status. Individuals should inform their physician concerning all medications they are taking, including those medications acquired by a prescription as well as over the counter medicines. The use of Cialis offers no protection against sexually transmitted diseases, including HIV. Patients should continue to use protective measures necessary to guard against these diseases. In case of an overdose, call your physician immediately.


Why is Cialis absolutely contraindicated in individuals who are currently taking medications containing nitrates?

Cialis may increase the hypotensive effects of nitrates to life threatening levels. Therefore, individuals who are currently using nitrates in any form even intermittently should not take Cialis. Nitrates are available in many medications; sprays, ointments, skin patches, pastes and tablets dissolved in the mouth. Nitrates are also found in illicit drugs such as amyl nitrate or nitrite "Poppers". If you are unsure if you are currently taking nitrates please value your health and consult with your local physician or pharmacist.


Can I use Cialis with other medications?

Yes, it is generally safe to use Cialis while on other medications, however some medicines may increase the effects of Cialis. Individuals should always consult with their healthcare provider prior to taking any medication. Note Cialis does have one absolute contraindication; individuals who are taking medication-containing nitrates (even intermittently) should not take Cialis.


Can I get Cialis over the counter?

No, Cialis should only be taken by prescription from a licensed physician. Regulations do not permit Cialis to be taken without prescription. Secondary to the advent of the internet individuals may now order Cialis online simply by completing an online medical questionnaire. Subsequently, a licensed physician will review your medical history and patient profile. If approved for a Cialis prescription, your order shipped discreetly to your home or office in 1-2 business days.

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